8SAC

Crystal Structure of Cystathionine beta lyase from Klebsiella aerogenes (P21212 form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Cystathionine beta-lyase	polymer	403	44102.2	4	UniProt (A0A0H3FMF8) Pfam (PF01053)	Klebsiella aerogenes KCTC 2190
2	E, G, I, K (A, B, C, D)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	4	Chemie (PLP)
3	F, H, J, L (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
4	M, N, O, P (A, B, C, D)	water	water		18.0	815	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 395 (UniProt: A0A0H3FMF8)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Ile 244	Val 244	engineered mutation
Pro 360	Leu 360	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	176409.0
Non-Polymers*	Number of molecules	8
	Total formula weight	1085.8
All*	Total formula weight	177494.8

*Water molecules are not included.