8S98
Crystal structure of the TYK2 pseudokinase domain in complex with compound 8
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Non-receptor tyrosine-protein kinase TYK2 | polymer | 295 | 33004.4 | 3 | UniProt (P29597) Pfam (PF07714) | Homo sapiens (human) | |
| 2 | D, E, F (A, B, C) | (8S)-N-cyclopropyl-5-[(2-methoxypyridin-3-yl)amino]-7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide | non-polymer | 353.4 | 3 | Chemie (ZRU) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 625 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 99013.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1060.1 | |
| All* | Total formula weight | 100073.5 |
