8S97

C143W variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	citrate synthase	polymer	379	41102.7	1	UniProt (A0A045JB88) Pfam (PF00285) UniProt (by SIFTS) (P9WPD3)	Mycobacterium tuberculosis H37Rv
2	B, C, D, E (A)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
3	F (A)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

A: 1 - 373 (UniProt: A0A045JB88)

PDB	External Database	Details
Trp 143	Cys 143	engineered mutation
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag
His 377	-	expression tag
His 378	-	expression tag
His 379	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41102.7
Non-Polymers*	Number of molecules	4
	Total formula weight	248.3
All*	Total formula weight	41350.9

*Water molecules are not included.