8S7D
Cryo-EM structure of SKP1-FBXO22 in complex with a BACH1 BTB dimer at 3.2A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Transcription regulator protein BACH1 | polymer | 125 | 14186.2 | 2 | UniProt (O14867) Pfam (PF00651) | Homo sapiens (human) | BTB and CNC homolog 1,HA2303 |
| 2 | C (C) | S-phase kinase-associated protein 1 | polymer | 163 | 18680.0 | 1 | UniProt (P63208) Pfam (PF03931) Pfam (PF01466) | Homo sapiens (human) | Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1 |
| 3 | D (D) | F-box only protein 22 | polymer | 395 | 43597.1 | 1 | UniProt (Q8NEZ5) Pfam (PF00646) Pfam (PF10442) | Homo sapiens (human) | F-box protein FBX22p44 |
Sequence modifications
A, B: 3 - 124 (UniProt: O14867)
D: 12 - 403 (UniProt: Q8NEZ5)
| PDB | External Database | Details |
|---|---|---|
| Gln 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Met 2 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Ser 11 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 90649.4 | |
| All* | Total formula weight | 90649.4 |
