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8S6Y

Co-crystal structure of TEAD1 with OPN-9652

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(AAA, BBB, CCC, DDD)
Transcriptional enhancer factor TEF-1polymer21725068.64UniProt (P28347)Homo sapiens (human)NTEF-1,Protein GT-IIC,TEA domain family member 1,TEAD-1,Transcription factor 13,TCF-13
2BA, E, OA, Q
(CCC, AAA, DDD, BBB)
1-[7-[3-fluoranyl-4-(trifluoromethyl)phenoxy]-3,4-dihydro-1~{H}-isoquinolin-2-yl]propan-1-onenon-polymer367.34Chemie (A1H5I)
3AA, CA, DA, EA, F...
(BBB, CCC, AAA, DDD)
1,2-ETHANEDIOLnon-polymer62.123Chemie (EDO)
4FA, G, GA, H, HA...
(CCC, AAA, DDD, BBB)
SULFATE IONnon-polymer96.112Chemie (SO4)
5O
(AAA)
GLYCEROLnon-polymer92.11Chemie (GOL)
6RA, X
(DDD, BBB)
DI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
7UA, VA, WA, XA
(AAA, BBB, CCC, DDD)
waterwater18.0591Chemie (HOH)
Sequence modifications
AAA, BBB, CCC, DDD: 208 - 426 (UniProt: P28347)
PDBExternal DatabaseDetails
-Ala 245deletion
-Asn 246deletion
Cys 248Ser 248conflict
Pro 249Tyr 249conflict
Ala 251Asp 251conflict
Pro 253Leu 253conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight100274.5
Non-Polymers*Number of molecules42
Total formula weight4354.0
All*Total formula weight104628.5
*Water molecules are not included.

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PDB entries from 2025-07-30

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