8S6F
A Structural Investigation of the Interaction between a GC-376-Based Peptidomimetic PROTAC and Its Precursor with the Viral Main Protease of Coxsackievirus B3
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Protease 3C | polymer | 180 | 19926.0 | 1 | UniProt (P03313) Pfam (PF00548) | Coxsackievirus B3 | Picornain 3C,P3C |
2 | B (A) | methyl (4~{S})-4-[[(2~{S})-4-methyl-2-(phenylmethoxycarbonylamino)pentanoyl]amino]-5-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]pentanoate | non-polymer | 461.6 | 1 | Chemie (VQR) | |||
3 | C (A) | water | water | 18.0 | 65 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19926.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 461.6 | |
All* | Total formula weight | 20387.5 |