8S1C

Intertwined dimer of the PTK6 SH3 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Protein-tyrosine kinase 6	polymer	71	8439.3	2	UniProt (Q13882) Pfam (PF00018)	Homo sapiens (human)	Breast tumor kinase,Tyrosine-protein kinase BRK
2	C, D, E, F, G... (A, B)	SODIUM ION	non-polymer		23.0	12	Chemie (NA)
3	M, N, Q, R (A, B)	CHLORIDE ION	non-polymer		35.5	4	Chemie (CL)
4	S, T (A, B)	water	water		18.0	136	Chemie (HOH)

Sequence modifications

A, B: 11 - 72 (UniProt: Q13882)

PDB	External Database	Details
Met 10	-	initiating methionine
Leu 73	-	expression tag
Glu 74	-	expression tag
His 75	-	expression tag
His 76	-	expression tag
His 77	-	expression tag
His 78	-	expression tag
His 79	-	expression tag
His 80	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	16878.6
Non-Polymers*	Number of molecules	16
	Total formula weight	417.7
All*	Total formula weight	17296.3

*Water molecules are not included.