8S0N
Crystal structure of the TMPRSS2 zymogen in complex with the nanobody A07
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, C) | Transmembrane protease serine 2 | polymer | 397 | 43922.4 | 2 | UniProt (O15393) Pfam (PF15494) Pfam (PF00089) | Homo sapiens (human) | Serine protease 10 |
| 2 | B, C (B, D) | nanobody A07 | polymer | 150 | 16031.5 | 2 | Vicugna pacos | ||
| 3 | E, F, G, H (A, B, D, C) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A, C: 107 - 492 (UniProt: O15393)
| PDB | External Database | Details |
|---|---|---|
| Arg 105 | - | expression tag |
| Ser 106 | - | expression tag |
| Ala 441 | Ser 441 | engineered mutation |
| Gly 493 | - | expression tag |
| Pro 494 | - | expression tag |
| Phe 495 | - | expression tag |
| Glu 496 | - | expression tag |
| Asp 497 | - | expression tag |
| Asp 498 | - | expression tag |
| Asp 499 | - | expression tag |
| Asp 500 | - | expression tag |
| Lys 501 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 119907.9 | |
| All* | Total formula weight | 119907.9 |
