8S0D
H. sapiens MCM bound to double stranded DNA and ORC1-6
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | Origin recognition complex subunit 6 | polymer | 251 | 28017.7 | 1 | UniProt (Q9Y5N6) Pfam (PF05460) Pfam (PF21913) | Homo sapiens (human) | |
| 2 | B (2) | DNA replication licensing factor MCM2 | polymer | 902 | 101758.8 | 1 | UniProt (P49736) Pfam (PF12619) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | Minichromosome maintenance protein 2 homolog,Nuclear protein BM28 |
| 3 | C (3) | DNA replication licensing factor MCM3 | polymer | 810 | 91297.0 | 1 | UniProt (P25205) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | DNA polymerase alpha holoenzyme-associated protein P1,P1-MCM3,RLF subunit beta,p102 |
| 4 | D (4) | DNA replication licensing factor MCM4 | polymer | 863 | 96702.9 | 1 | UniProt (P33991) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | CDC21 homolog,P1-CDC21 |
| 5 | E (5) | DNA replication licensing factor MCM5 | polymer | 734 | 82406.6 | 1 | UniProt (P33992) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF21933) | Homo sapiens (human) | CDC46 homolog,P1-CDC46 |
| 6 | F (6) | DNA replication licensing factor MCM6 | polymer | 821 | 93010.3 | 1 | UniProt (Q14566) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) Pfam (PF18263) | Homo sapiens (human) | p105MCM |
| 7 | G (7) | DNA replication licensing factor MCM7 | polymer | 719 | 81411.9 | 1 | UniProt (P33993) Pfam (PF14551) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | CDC47 homolog,P1.1-MCM3 |
| 8 | H (X) | DNA (58-mer) | polymer | 58 | 17790.4 | 1 | synthetic construct | ||
| 9 | I (Y) | DNA (58-mer) | polymer | 58 | 17955.5 | 1 | synthetic construct | ||
| 10 | J (A) | Origin recognition complex subunit 1 | polymer | 861 | 97499.9 | 1 | UniProt (Q13415) Pfam (PF01426) Pfam (PF00004) Pfam (PF17872) Pfam (PF09079) | Homo sapiens (human) | Replication control protein 1 |
| 11 | K (B) | Origin recognition complex subunit 2 | polymer | 577 | 66063.4 | 1 | UniProt (Q13416) Pfam (PF04084) | Homo sapiens (human) | |
| 12 | L (C) | Isoform 2 of Origin recognition complex subunit 3 | polymer | 712 | 82436.1 | 1 | UniProt (Q9UBD5) Pfam (PF07034) Pfam (PF19675) Pfam (PF18137) | Homo sapiens (human) | Origin recognition complex subunit Latheo |
| 13 | M (D) | Origin recognition complex subunit 4 | polymer | 436 | 50443.3 | 1 | UniProt (O43929) Pfam (PF13191) Pfam (PF14629) | Homo sapiens (human) | |
| 14 | N (E) | Origin recognition complex subunit 5 | polymer | 435 | 50349.9 | 1 | UniProt (O43913) Pfam (PF13191) Pfam (PF21639) Pfam (PF14630) | Homo sapiens (human) | |
| 15 | CA, FA, HA, O, Y (7, D, E, 2, 6) | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 5 | Chemie (AGS) | |||
| 16 | BA, DA, GA, IA, P... (7, D, E, 2, 3...) | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 17 | AA, EA, Q, T, X (6, 7, 2, 4, 5) | ZINC ION | non-polymer | 65.4 | 5 | Chemie (ZN) | |||
| 18 | R, U, V (3, 4, 5) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) |
Sequence modifications
3: 1 - 808 (UniProt: P25205)
4: 1 - 863 (UniProt: P33991)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Glu 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 650 | Leu 650 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 957143.7 | |
| Non-Polymers* | Number of molecules | 21 |
| Total formula weight | 4419.3 | |
| All* | Total formula weight | 961563.0 |
