8S00

CpKRS complexed with lysine and an inhibitor

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Lysine--tRNA ligase	polymer	535	61459.1	2	UniProt (Q5CR27) Pfam (PF01336) Pfam (PF00152)	Cryptosporidium parvum Iowa	Lysyl-tRNA synthetase
2	C, J (A, B)	LYSINE	non-polymer		147.2	2	Chemie (LYS)
3	D, K (A, B)	6-oxidanyl-~{N}-[(1-oxidanylcyclohexyl)methyl]-4-oxidanylidene-chromene-2-carboxamide	non-polymer		317.3	2	Chemie (A1H4W)
4	E, L (A, B)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	2	Chemie (TRS)
5	F, G, H, I, M (A, B)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
6	N, O (A, B)	water	water		18.0	696	Chemie (HOH)

Sequence modifications

A, B: 46 - 559 (UniProt: Q5CR27)

PDB	External Database	Details
Met 25	-	initiating methionine
Ala 26	-	expression tag
His 27	-	expression tag
His 28	-	expression tag
His 29	-	expression tag
His 30	-	expression tag
His 31	-	expression tag
His 32	-	expression tag
Met 33	-	expression tag
Gly 34	-	expression tag
Thr 35	-	expression tag
Leu 36	-	expression tag
Glu 37	-	expression tag
Ala 38	-	expression tag
Gln 39	-	expression tag
Thr 40	-	expression tag
Gln 41	-	expression tag
Gly 42	-	expression tag
Pro 43	-	expression tag
Gly 44	-	expression tag
Ser 45	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	122918.2
Non-Polymers*	Number of molecules	11
	Total formula weight	1633.8
All*	Total formula weight	124552.0

*Water molecules are not included.