8RYO

Structure of S2-198 TCR in complex with HLA-A*03:01 bound to ELFSYLIEK peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	HLA class I histocompatibility antigen, A alpha chain	polymer	276	31855.1	1	UniProt (P04439) Pfam (PF00129) Pfam (PF07654) In PDB	Homo sapiens (human)	Human leukocyte antigen A,HLA-A
2	B	Beta-2-microglobulin	polymer	100	11879.4	1	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (human)
3	C	ELFSYLIEK peptide	polymer	9	1142.3	1		Homo sapiens
4	D	TCR alpha	polymer	198	21730.2	1		Homo sapiens
5	E	TCR beta	polymer	245	27556.7	1		Homo sapiens
6	A	2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL	non-polymer		164.2	1	Chemie (TOE)
7	B, D	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
8	B	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
9		water	water		18.0	249	Chemie (HOH)

Sequence modifications

A: 1 - 275 (UniProt: P04439)

PDB	External Database	Details
Pro 276	-	expression tag

B: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	94163.7
Non-Polymers*	Number of molecules	4
	Total formula weight	383.3
All*	Total formula weight	94547.0

*Water molecules are not included.