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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8RXH

CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME WITH A/P/E-site tRNA AND mRNA : PARENTAL STRAIN

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1L1LSUa_rRNA_chain_1polymer1782577073.61Leishmania major strain Friedlin
2L2LSUb_rRNA_chain_2polymer1526492586.01Leishmania major strain Friedlin
3L3SR1_chain_3polymer21669146.61GenBank (321438308)Leishmania major strain Friedlin
4L4SR2_chain_4polymer18459466.31Leishmania major strain Friedlin
5L5SR4_chain_5polymer13543503.81Leishmania major strain Friedlin
6L6SR6_chain_6polymer7323336.91GenBank (321438308)Leishmania major strain Friedlin
7L75.8S_rRNA_chain_7polymer17154975.51GenBank (2105481105)Leishmania major strain Friedlin
8L85S_rRNA_chain_8polymer12439756.61Leishmania major strain Friedlin
9LAPutative 60S ribosomal protein L2polymer26028331.91UniProt (Q4FWX5)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Leishmania major strain Friedlin
10LBPutative ribosomal protein L3polymer41947593.71UniProt (Q4Q2Q6)
Pfam (PF00297)
In PDB		Leishmania major strain Friedlin
11LCPutative ribosomal protein L1apolymer37341096.91UniProt (E9ADW5)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Leishmania major strain Friedlin
12LD60S ribosomal protein L11polymer18821694.51UniProt (P48157)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Leishmania major strain Friedlin
13LEPutative 60S ribosomal protein L9polymer19021594.31UniProt (Q4QC91)
Pfam (PF00347)
In PDB		Leishmania major strain Friedlin
14LFPutative 60S ribosomal protein L6polymer19521126.71UniProt (Q4Q4D3)
Pfam (PF01159)
In PDB		Leishmania major strain Friedlin
15LG60S ribosomal protein L7apolymer26429824.21UniProt (Q4QIP1)
Pfam (PF01248)
In PDB		Leishmania major strain Friedlin
16LHPutative 60S ribosomal protein L13apolymer22225509.21UniProt (Q4QFG2)
Pfam (PF00572)
In PDB		Leishmania major strain Friedlin
17LIPutative 60S ribosomal protein L13polymer22024849.01UniProt (E9AEA8)
Pfam (PF01294)
In PDB		Leishmania major strain Friedlin
18LJPutative 60S ribosomal protein L23polymer13914982.61UniProt (E9AFK3)
Pfam (PF00238)
In PDB		Leishmania major strain Friedlin
19LKPutative 40S ribosomal protein L14polymer17519948.61UniProt (Q4QBJ1)
Pfam (PF00467)
Pfam (PF01929)
In PDB		Leishmania major strain Friedlin
20LLPutative 60S ribosomal protein L27A/L29polymer14516135.91UniProt (E9AFK0)
Pfam (PF00828)
In PDB		Leishmania major strain Friedlin
21LMRibosomal protein L15polymer20424498.01UniProt (Q4Q6S3)
Pfam (PF00827)
In PDB		Leishmania major strain Friedlin
22LNPutative 60S ribosomal protein L10polymer21324607.21UniProt (O97213)
Pfam (PF00252)
In PDB		Leishmania major strain Friedlin
23LOPutative 60S ribosomal protein L5polymer30534058.61UniProt (E9AF09)
Pfam (PF17144)
Pfam (PF14204)
In PDB		Leishmania major strain Friedlin
24LP60S ribosomal protein L18polymer19822071.11UniProt (Q4QG98)
Pfam (PF17135)
In PDB		Leishmania major strain Friedlin
25LQPutative 60S ribosomal protein L19polymer25428896.11UniProt (Q4QJ37)
Pfam (PF01280)
In PDB		Leishmania major strain Friedlin
26LR60S ribosomal protein L18apolymer17920852.31UniProt (Q4Q5J4)
Pfam (PF01775)
In PDB		Leishmania major strain Friedlin
27LSPutative 60S ribosomal protein L21polymer15918068.21UniProt (Q4QEX4)
Pfam (PF01157)
In PDB		Leishmania major strain Friedlin
28LTPutative 60S ribosomal protein L17polymer16619124.51UniProt (Q4QAX6)
Pfam (PF00237)
In PDB		Leishmania major strain Friedlin
29LUPutative 60S ribosomal protein L22polymer12915030.51UniProt (Q4Q0X2)
Pfam (PF01776)
In PDB		Leishmania major strain Friedlin
30LVPutative 60S ribosomal protein L23apolymer14516372.41UniProt (Q4QJ20)
Pfam (PF00276)
In PDB		Leishmania major strain Friedlin
31LWPutative 60S ribosomal protein L26polymer14316217.11UniProt (Q4QAC5)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Leishmania major strain Friedlin
32LXPutative ribosomal protein L24polymer12414608.21UniProt (Q4Q1W6)
Pfam (PF01246)
In PDB		Leishmania major strain Friedlin
33LY60S ribosomal protein L27polymer13415469.31UniProt (Q4Q504)
Pfam (PF00467)
Pfam (PF01777)
In PDB		Leishmania major strain Friedlin
34LZPutative 60S ribosomal protein L28polymer14716314.91UniProt (Q4QGW7)
Pfam (PF01778)
In PDB		Leishmania major strain Friedlin
35LaPutative 60S ribosomal protein L35polymer12715262.21UniProt (Q4Q8V7)
Pfam (PF00831)
In PDB		Leishmania major strain Friedlin
36Lb60S ribosomal protein L29polymer708001.31UniProt (Q4Q178)
Pfam (PF01779)
In PDB		Leishmania major strain Friedlin
37LcPutative 60S ribosomal protein L7polymer25228900.01UniProt (Q4Q9H4)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Leishmania major strain Friedlin
38Ld60S ribosomal protein L30polymer10411370.21UniProt (E9AEK1)
Pfam (PF01248)
In PDB		Leishmania major strain Friedlin
39LePutative 60S ribosomal subunit protein L31polymer18821316.31UniProt (E9AFF2)
Pfam (PF01198)
In PDB		Leishmania major strain Friedlin
40Lf60S ribosomal protein L32polymer13315458.21UniProt (Q4QC11)
Pfam (PF01655)
In PDB		Leishmania major strain Friedlin
41LgPutative ribosomal protein l35apolymer14416492.31UniProt (Q4QHL3)
Pfam (PF01247)
In PDB		Leishmania major strain Friedlin
42LhPutative 60S ribosomal protein L34polymer16819335.11UniProt (Q4QDP9)
Pfam (PF01199)
In PDB		Leishmania major strain Friedlin
43LiPutative 60S Ribosomal protein L36polymer10511975.21UniProt (Q4QCE1)
Pfam (PF01158)
In PDB		Leishmania major strain Friedlin
44LjRibosomal protein L37polymer839862.61UniProt (E9AEH2)
Pfam (PF01907)
In PDB		Leishmania major strain Friedlin
45LkPutative ribosomal protein L38polymer839479.31UniProt (Q4Q8X0)
Pfam (PF01781)
In PDB		Leishmania major strain Friedlin
46LlPutative 60S ribosomal protein L39polymer516504.81UniProt (Q4QEQ0)
Pfam (PF00832)
In PDB		Leishmania major strain Friedlin
47LmUbiquitin-60S ribosomal protein L40polymer12814711.41UniProt (P69201)
Pfam (PF00240)
Pfam (PF01020)
In PDB		Leishmania major strain Friedlin
48Ln60S ribosomal protein L41polymer344390.51Leishmania major strain Friedlin
49Lo60S ribosomal protein L37apolymer9210337.21UniProt (Q4QC01)
Pfam (PF01780)
In PDB		Leishmania major strain FriedlinPutative 60S ribosomal protein L37a
50LpPutative 60S ribosomal protein L44polymer10612302.71UniProt (Q4Q3L3)
Pfam (PF00935)
In PDB		Leishmania major strain Friedlin
51S1SSU_rRNA_chain_S1polymer2204710670.81Leishmania major strain Friedlin
52S2A-site_tRNA_chain_S2polymer7624599.71Leishmania major strain Friedlin
53S3P-site_tRNA_chain_S3polymer7724786.81Leishmania major strain Friedlin
54S4E-site_tRNA_chain_S4polymer7624485.51Leishmania major strain Friedlin
55S5mRNA_chain_S5polymer134085.51Leishmania major strain Friedlin
56SA40S ribosomal protein S3apolymer26430062.01UniProt (Q4FX73)
Pfam (PF01015)
In PDB		Leishmania major strain FriedlinLmS3a-related protein,LmS3arp
57SB40S ribosomal protein SApolymer24627536.61UniProt (Q4Q0Q0)
Pfam (PF00318)
In PDB		Leishmania major strain Friedlin
58SCPutative 40S ribosomal protein S3polymer21924511.81UniProt (Q4Q4A0)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Leishmania major strain Friedlin
59SDPutative 40S ribosomal protein S9polymer19022188.91UniProt (Q4QIM3)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Leishmania major strain Friedlin
60SE40S ribosomal protein S4polymer27330742.11UniProt (Q4QG31)
Pfam (PF08071)
Pfam (PF01479)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Leishmania major strain Friedlin
61SF40S ribosomal protein S2polymer26528791.11UniProt (Q4QDL5)
Pfam (PF00333)
Pfam (PF03719)
In PDB		Leishmania major strain Friedlin
62SG40S ribosomal protein S6polymer24928370.21UniProt (Q9NE83)
Pfam (PF01092)
In PDB		Leishmania major strain Friedlin
63SH40S ribosomal protein S5polymer19021336.61UniProt (Q868B1)
Pfam (PF00177)
In PDB		Leishmania major strain Friedlin40S ribosomal protein S5A,40S ribosomal protein S5B
64SI40S ribosomal protein S7polymer20023765.21UniProt (E9AC32)
Pfam (PF01251)
In PDB		Leishmania major strain Friedlin
65SJPutative 40S ribosomal protein S15Apolymer13014719.31UniProt (Q4QGW3)
Pfam (PF00410)
In PDB		Leishmania major strain Friedlin
66SK40S ribosomal protein S8polymer22024984.31UniProt (P25204)
Pfam (PF01201)
In PDB		Leishmania major strain Friedlin
67SLPutative 40S ribosomal protein S16polymer14916718.61UniProt (Q4Q9A5)
Pfam (PF00380)
In PDB		Leishmania major strain FriedlinRibosomal protein S16
68SMPutative ribosomal protein S20polymer11613032.01UniProt (Q4Q8G4)
Pfam (PF00338)
In PDB		Leishmania major strain Friedlin
69SNPutative 40S ribosomal protein S10polymer16818681.11UniProt (Q4Q1X7)
Pfam (PF03501)
In PDB		Leishmania major strain Friedlin
70SO40S ribosomal protein S14polymer14415623.21UniProt (Q4Q8H1)
Pfam (PF00411)
In PDB		Leishmania major strain Friedlin
71SPPutative 40S ribosomal protein S23polymer14315969.61UniProt (Q4QC89)
Pfam (PF00164)
In PDB		Leishmania major strain Friedlin
72SQ40S ribosomal protein S12polymer14115627.81UniProt (Q4QG97)
Pfam (PF01248)
In PDB		Leishmania major strain Friedlin
73SRPutative 40S ribosomal protein S18polymer15317433.41UniProt (Q4Q1Y3)
Pfam (PF00416)
In PDB		Leishmania major strain FriedlinRibosomal protein S18
74SSPutative ribosomal protein S29polymer576696.91UniProt (Q4Q817)
Pfam (PF00253)
In PDB		Leishmania major strain Friedlin
75STPutative 40S ribosomal protein S13polymer15117482.81UniProt (Q4Q3M1)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Leishmania major strain Friedlin
76SURibosomal protein S17 family proteinpolymer17320023.51Leishmania major strain Friedlin
77SVPutative 40S ribosomal protein S17polymer14316551.51UniProt (Q4Q806)
Pfam (PF00833)
In PDB		Leishmania major strain Friedlin
78SWPutative 40S ribosomal protein S15polymer15217472.41UniProt (Q4QBV0)
Pfam (PF00203)
In PDB		Leishmania major strain Friedlin
79SX40S ribosomal protein S19-like proteinpolymer16118158.11UniProt (E9AEE8)
Pfam (PF01090)
In PDB		Leishmania major strain Friedlin
80SYPutative 40S ribosomal protein S21polymer16417035.61UniProt (Q4QH01)
Pfam (PF01249)
In PDB		Leishmania major strain Friedlin
81SZ40S ribosomal protein S24polymer13715808.91UniProt (Q4Q1D2)
Pfam (PF01282)
In PDB		Leishmania major strain Friedlin
82Sa40S ribosomal protein S25polymer12013071.41UniProt (Q4Q9X4)
Pfam (PF03297)
In PDB		Leishmania major strain Friedlin
83Sb40S ribosomal protein S26polymer11212794.31UniProt (Q4Q8L6)
Pfam (PF01283)
In PDB		Leishmania major strain Friedlin
84ScPutative 40S ribosomal protein S27-1polymer869819.51UniProt (Q4Q140)
Pfam (PF01667)
In PDB		Leishmania major strain Friedlin
85SdPutative 40S ribosomal protein S33polymer879763.21UniProt (Q4Q931)
Pfam (PF01200)
In PDB		Leishmania major strain Friedlin
86Se40S ribosomal protein S30polymer667394.91UniProt (Q4Q7P0)
Pfam (PF04758)
In PDB		Leishmania major strain Friedlin
87SfUbiquitin-60S ribosomal protein L40polymer15217062.81UniProt (Q4QFK7)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Leishmania major strain Friedlin
88SgGuanine nucleotide-binding protein subunit beta-like proteinpolymer31234441.51UniProt (Q4Q7Y7)
Pfam (PF00400)
In PDB		Leishmania major strain Friedlin
89ShPutative RNA binding proteinpolymer23525229.31UniProt (Q4Q5K7)
Pfam (PF00076)
In PDB		Leishmania major strain Friedlin
90L1, L2, S1, L3, L6...MAGNESIUM IONnon-polymer24.3289Chemie (MG)
91L1, L2, L5, LA, S1...SODIUM IONnon-polymer23.086Chemie (NA)
92L1, L2, S1, LB, L7...POTASSIUM IONnon-polymer39.1143Chemie (K)
93L2(2S)-2-[2-[4-[[(2R,3S,4S)-3-acetyloxy-4-oxidanyl-pyrrolidin-2-yl]methyl]phenoxy]ethanoylamino]-6-azanyl-hexanoic acidnon-polymer437.51Chemie (A1H4F)
94LpZINC IONnon-polymer65.41Chemie (ZN)
95waterwater18.0413Chemie (HOH)
Sequence modifications
LI: 1 - 220 (UniProt: E9AEA8)
PDBExternal DatabaseDetails
Arg 203Asn 203conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains89
Total formula weight3611949.3
Non-Polymers*Number of molecules520
Total formula weight15095.2
All*Total formula weight3627044.5
*Water molecules are not included.

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PDB entries from 2024-10-09

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