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8RX3

LTA4 hydrolase in complex with CTX-4430

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ALeukotriene A-4 hydrolasepolymer61369444.01UniProt (P09960)
Pfam (PF17900)
Pfam (PF01433)
Pfam (PF09127)
In PDB
Homo sapiens (human)LTA-4 hydrolase,Leukotriene A(4) hydrolase
2AZINC IONnon-polymer65.41Chemie (ZN)
3AACETATE IONnon-polymer59.01Chemie (ACT)
4AYTTERBIUM (III) IONnon-polymer173.02Chemie (YB)
5AIMIDAZOLEnon-polymer69.12Chemie (IMD)
6A4-[[(1~{S},4~{S})-5-[[4-[4-(1,3-oxazol-2-yl)phenoxy]phenyl]methyl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]benzoic acidnon-polymer481.51Chemie (A1H3T)
7waterwater18.0669Chemie (HOH)
Sequence modifications
A: 1 - 610 (UniProt: P09960)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight69444.0
Non-Polymers*Number of molecules7
Total formula weight1090.2
All*Total formula weight70534.2
*Water molecules are not included.

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PDB entries from 2024-05-15

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