8RVR

Crystal structure of Trypanosoma congolense pyruvate kinase in complex with a single-domain antibody (TcoPYK-sdAb42) in the presence of sulfate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Pyruvate kinase	polymer	514	56424.3	6	UniProt (G0UYF4) Pfam (PF00224) Pfam (PF02887)	Trypanosoma congolense
2	G, H, I, J, K... (G, H, I, J, K...)	Camelid single-domain antibody 42 (sdAb42)	polymer	149	16416.8	6		Vicugna pacos
3	BA, CA, M, N, V... (E, F, A, B, C...)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
4	AA, DA, EA, FA, GA... (E, G, H, I, J...)	GLYCEROL	non-polymer		92.1	13	Chemie (GOL)
5	R, W (C, D)	GLUTAMIC ACID	non-polymer		147.1	2	Chemie (GLU)
6	HA, IA, JA, KA, LA... (A, B, C, D, E...)	water	water		18.0	123	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F: 1 - 499 (UniProt: G0UYF4)

PDB	External Database	Details
Glu 500	-	expression tag
Asn 501	-	expression tag
Leu 502	-	expression tag
Tyr 503	-	expression tag
Phe 504	-	expression tag
Gln 505	-	expression tag
Ser 506	-	expression tag
Gly 507	-	expression tag
Gly 508	-	expression tag
His 509	-	expression tag
His 510	-	expression tag
His 511	-	expression tag
His 512	-	expression tag
His 513	-	expression tag
His 514	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	437046.8
Non-Polymers*	Number of molecules	21
	Total formula weight	2067.9
All*	Total formula weight	439114.6

*Water molecules are not included.