8RV8

SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 5

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	2'-O-methyltransferase nsp16	polymer	302	33701.6	1	UniProt (P0DTD1) Pfam (PF06460) In PDB	Severe acute respiratory syndrome coronavirus 2	Non-structural protein 16,nsp16
2	B	Non-structural protein 10	polymer	142	15078.3	1	UniProt (P0DTC1) Pfam (PF09401) In PDB	Severe acute respiratory syndrome coronavirus 2	nsp10,Growth factor-like peptide,GFL
3	A	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	1	Chemie (MES)
4	A	5-[[(2~{S},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanyl]-2-chloranyl-benzoic acid	non-polymer		437.9	1	Chemie (A1H28)
5	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
7		water	water		18.0	298	Chemie (HOH)

Sequence modifications

A: 1 - 298 (UniProt: P0DTD1)

PDB	External Database	Details
Gly -3	-	expression tag
Ser -2	-	expression tag
Met -1	-	expression tag
Ala 0	-	expression tag

B: 1 - 139 (UniProt: P0DTC1)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	48779.9
Non-Polymers*	Number of molecules	6
	Total formula weight	948.1
All*	Total formula weight	49728.0

*Water molecules are not included.