8RV2
Structure of the formin INF2 bound to the barbed end of F-actin.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Actin, alpha skeletal muscle | polymer | 375 | 41875.6 | 4 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (rabbit) | Alpha-actin-1 |
| 2 | E, F (E, F) | Isoform 2 of Inverted formin-2 | polymer | 777 | 84453.7 | 2 | UniProt (Q27J81) Pfam (PF02181) Pfam (PF02205) | Homo sapiens (human) | HBEBP2-binding protein C |
| 3 | G, I, L (A, B, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 4 | H, J, M, O (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 5 | K (B) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | N (D) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) |
Sequence modifications
E, F: 469 - 1240 (UniProt: Q27J81)
| PDB | External Database | Details |
|---|---|---|
| Gly 464 | - | expression tag |
| Gly 465 | - | expression tag |
| Gly 466 | - | expression tag |
| Gly 467 | - | expression tag |
| Gly 468 | - | expression tag |
| Ser 488 | Pro 488 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 336410.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1981.0 | |
| All* | Total formula weight | 338390.9 |
