8RUP
Chromosome Passenger Complex (CPC) localization module in complex with H3.T3p-nucleosome
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histone H3.2 | polymer | 136 | 15435.1 | 1 | UniProt (P84233) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 2 | B, F (B, F) | Histone H4 | polymer | 103 | 11394.4 | 2 | UniProt (P62799) Pfam (PF15511) | Xenopus laevis (African clawed frog) | |
| 3 | C, G (C, G) | Histone H2A type 1 | polymer | 130 | 14109.4 | 2 | UniProt (P06897) Pfam (PF00125) Pfam (PF16211) | Xenopus laevis (African clawed frog) | |
| 4 | D, H (D, H) | Histone H2B 1.1 | polymer | 123 | 13655.9 | 2 | UniProt (P02281) Pfam (PF00125) | Xenopus laevis (African clawed frog) | H2B1.1 |
| 5 | E (E) | Histone H3 | polymer | 135 | 15383.9 | 1 | UniProt (A0A310TTQ1) Pfam (PF00125) | Xenopus laevis (African clawed frog) | |
| 6 | I (I) | DNA (147-MER) | polymer | 152 | 47128.0 | 1 | synthetic construct | ||
| 7 | J (J) | DNA (147-MER) | polymer | 152 | 46709.8 | 1 | synthetic construct | ||
| 8 | K (K) | Baculoviral IAP repeat-containing protein 5 | polymer | 144 | 16568.9 | 1 | UniProt (O15392) Pfam (PF00653) | Homo sapiens (human) | Apoptosis inhibitor 4,Apoptosis inhibitor survivin |
| 9 | L (L) | Borealin | polymer | 76 | 9138.7 | 1 | UniProt (Q53HL2) Pfam (PF10444) | Homo sapiens (human) | Cell division cycle-associated protein 8,Dasra-B,hDasra-B,Pluripotent embryonic stem cell-related gene 3 protein |
| 10 | M (M) | Inner centromere protein | polymer | 82 | 9783.2 | 1 | UniProt (Q9NQS7) Pfam (PF12178) | Homo sapiens (human) | |
| 11 | N (K) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence modifications
A: 0 - 135 (UniProt: P84233)
C, G: 0 - 129 (UniProt: P06897)
D, H: 4 - 125 (UniProt: P02281)
K: 1 - 142 (UniProt: O15392)
M: 1 - 80 (UniProt: Q9NQS7)
| PDB | External Database | Details |
|---|---|---|
| Ala 102 | Gly 103 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Arg 99 | Gly 100 | conflict |
| Ser 123 | Ala 124 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 3 | - | initiating methionine |
| Thr 32 | Ser 33 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 13 |
| Total formula weight | 238467.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 65.4 | |
| All* | Total formula weight | 238532.6 |
