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8RTN

Human thrombin in complex with a trivalent inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(L, H)
Prothrombinpolymer62270122.82UniProt (P00734)
Pfam (PF00594)
Pfam (PF00051)
Pfam (PF09396)
Pfam (PF00089)
Homo sapiens (human)Coagulation factor II
2C
(I)
Synthetic trivalent inhibitorpolymer485357.51Glossina morsitans morsitans
3D
(H)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.21Chemie (NAG)
4E
(H)
SODIUM IONnon-polymer23.01Chemie (NA)
5F, G, H
(L, H, I)
waterwater18.0117Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight145603.2
Non-Polymers*Number of molecules2
Total formula weight244.2
All*Total formula weight145847.4
*Water molecules are not included.

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PDB entries from 2025-12-24

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