8RS8
Crystal structure of BRCA1 BRCTs in complex with a RIF1 phosphopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Breast cancer type 1 susceptibility protein | polymer | 217 | 24772.5 | 4 | UniProt (P38398) | Homo sapiens (human) | RING finger protein 53,RING-type E3 ubiquitin transferase BRCA1 |
| 2 | E, F, G, H (E, F, G, H) | Telomere-associated protein RIF1 | polymer | 11 | 1260.3 | 4 | UniProt (Q5UIP0) | Homo sapiens | Rap1-interacting factor 1 homolog |
| 3 | AA, BA, CA, DA, EA... (C, A, D, B, G) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 37 | Chemie (EDO) | |||
| 4 | LA, Y (C, B) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 5 | KA (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | AB, BB, CB, DB, WA... (E, F, G, H, A...) | water | water | 18.0 | 1001 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1646 - 1859 (UniProt: P38398)
| PDB | External Database | Details |
|---|---|---|
| Gly 1643 | - | expression tag |
| Pro 1644 | - | expression tag |
| Ser 1645 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 104131.2 | |
| Non-Polymers* | Number of molecules | 40 |
| Total formula weight | 2540.8 | |
| All* | Total formula weight | 106672.0 |
