8RRK
14-3-3 sigma complexed with an optimized phosphopeptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | 14-3-3 protein sigma | polymer | 252 | 28137.5 | 2 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | C, D (C, D) | phosphopeptide designed according to the 14-3-3 binding consensus | polymer | 10 | 1113.2 | 2 | synthetic construct | ||
| 3 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | F, G, H, J (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 5 | I (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 278 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 248 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 58501.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 499.9 | |
| All* | Total formula weight | 59001.3 |
