8RQX
Erk2 MAP kinase R65S+T188D - AMP-PNP complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 365 | 42174.4 | 1 | UniProt (P63086) Pfam (PF00069) | Rattus norvegicus (Norway rat) | MAP kinase 1,MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAP kinase 2,MAPK 2 |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | C (A) | water | water | 18.0 | 130 | Chemie (HOH) |
Sequence modifications
A: 1 - 358 (UniProt: P63086)
| PDB | External Database | Details |
|---|---|---|
| Ala -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
| Ser 65 | Arg 65 | engineered mutation |
| Asp 188 | Thr 188 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42174.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 506.2 | |
| All* | Total formula weight | 42680.6 |
