8RQQ

In meso structure of the adenosine A2a G protein-coupled receptor, A2aR, in 7.10 monoacylglycerol

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adenosine receptor A2a,Soluble cytochrome b562	polymer	447	49974.3	1	UniProt (P29274) UniProt (P0ABE7) Pfam (PF00001)	Homo sapiens (human)	Cytochrome b-562
2	B (A)	4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol	non-polymer		337.3	1	Chemie (ZMA)
3	C, D, E (A)	CHOLESTEROL	non-polymer		386.7	3	Chemie (CLR)
4	F, G, H, I, J... (A)	7.10 monoacylglycerol (S-form)	non-polymer		342.5	8	Chemie (A1H2K)
5	K (A)	7.10 monoacylglycerol (R-form)	non-polymer		342.5	1	Chemie (A1H52)
6	N, O (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
7	Q (A)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
8	R (A)	water	water		18.0	36	Chemie (HOH)

Sequence modifications

A: 2 - 208 (UniProt: P29274)

PDB	External Database	Details
Met -24	-	initiating methionine
Lys -23	-	expression tag
Thr -22	-	expression tag
Ile -21	-	expression tag
Ile -20	-	expression tag
Ala -19	-	expression tag
Leu -18	-	expression tag
Ser -17	-	expression tag
Tyr -16	-	expression tag
Ile -15	-	expression tag
Phe -14	-	expression tag
Cys -13	-	expression tag
Leu -12	-	expression tag
Val -11	-	expression tag
Phe -10	-	expression tag
Ala -9	-	expression tag
Asp -8	-	expression tag
Tyr -7	-	expression tag
Lys -6	-	expression tag
Asp -5	-	expression tag
Asp -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Gly -1	-	expression tag
Ala 0	-	expression tag
Pro 1	-	expression tag

A: 219 - 316 (UniProt: P29274)

PDB	External Database	Details
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag
His 323	-	expression tag
His 324	-	expression tag
His 325	-	expression tag
His 326	-	expression tag

A: 1001 - 1106 (UniProt: P0ABE7)

PDB	External Database	Details
Trp 1007	Met 29	variant
Ile 1102	His 124	variant
Leu 1106	Arg 128	variant

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	49974.3
Non-Polymers*	Number of molecules	16
	Total formula weight	4787.1
All*	Total formula weight	54761.4

*Water molecules are not included.