8RQF
Cryo-EM structure of human NTCP-Bulevirtide complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium/bile acid cotransporter | polymer | 349 | 38149.9 | 1 | UniProt (Q14973) Pfam (PF01758) | Homo sapiens (human) | Cell growth-inhibiting gene 29 protein,Na(+)/bile acid cotransporter,Na(+)/taurocholate transport protein,Sodium/taurocholate cotransporting polypeptide,Solute carrier family 10 member 1 |
| 2 | B (H) | Heavy chain of Fab3 | polymer | 235 | 25198.0 | 1 | Homo sapiens | ||
| 3 | C (L) | Light chain of Fab3 | polymer | 215 | 23481.1 | 1 | Homo sapiens | ||
| 4 | D (K) | Fab-specific nanobody | polymer | 120 | 13118.4 | 1 | Lama glama | ||
| 5 | E (B) | Polymerase | polymer | 46 | 5136.5 | 1 | UniProt (A0A515J2X9) UniProt (by SIFTS) (Q76R62) | hepatitis B virus genotype C | |
| 6 | F (B) | N-tetradecanoylglycine | non-polymer | 285.4 | 1 | Chemie (BJU) | |||
| 7 | G (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence modifications
B: 3 - 48 (UniProt: A0A515J2X9)
| PDB | External Database | Details |
|---|---|---|
| Lys 46 | Gln 52 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 105083.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 285.4 | |
| All* | Total formula weight | 105369.3 |
