8RPT
Crystal structure of human DNPH1 mutant- D80A
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | polymer | 145 | 16150.2 | 2 | UniProt (O43598) Pfam (PF05014) | Homo sapiens (human) | c-Myc-responsive protein RCL |
| 2 | C, D, H, I, J... (B, A) | CHLORIDE ION | non-polymer | 35.5 | 8 | Chemie (CL) | |||
| 3 | E, N (B, A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 4 | F, G, O, P (B, A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | Q, R (B, A) | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
B, A: 20 - 162 (UniProt: O43598)
| PDB | External Database | Details |
|---|---|---|
| Gly 18 | - | expression tag |
| Met 19 | - | expression tag |
| Ala 80 | Asp 80 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32300.4 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 744.1 | |
| All* | Total formula weight | 33044.6 |
