8RPS
Crystal structure of human DNPH1 mutant- D80N bound to 5hmdUMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (C, A, B) | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | polymer | 145 | 16193.2 | 3 | UniProt (O43598) Pfam (PF05014) | Homo sapiens (human) | c-Myc-responsive protein RCL |
| 2 | D, E (C, A) | 5-HYDROXYMETHYLURIDINE-2'-DEOXY-5'-MONOPHOSPHATE | non-polymer | 338.2 | 2 | Chemie (5HU) | |||
| 3 | F, G, H (C, A, B) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
C, A, B: 20 - 162 (UniProt: O43598)
| PDB | External Database | Details |
|---|---|---|
| Gly 18 | - | expression tag |
| Met 19 | - | expression tag |
| Asn 80 | Asp 80 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 48579.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 676.4 | |
| All* | Total formula weight | 49256.1 |
