8RPL

AMP-forming acetyl-CoA synthetase from Chloroflexota bacterium with bound acetyl AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Acetate--CoA ligase	polymer	657	74116.5	4	UniProt (A0A535FEC2) UniProt (by SIFTS) (A0ACD6BAL5)	Chloroflexota bacterium
2	E, H, K, N (A, B, C, D)	[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] ethanoate	non-polymer		389.3	4	Chemie (6R9)
3	F, I, L, O (A, B, C, D)	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID	non-polymer		238.3	4	Chemie (EPE)
4	G, J, M (A, B, C)	MAGNESIUM ION	non-polymer		24.3	3	Chemie (MG)
5	P (D)	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
6	Q, R, S, T (A, B, C, D)	water	water		18.0	181	Chemie (HOH)

Sequence modifications

A, B, C, D: 2 - 647 (UniProt: A0A535FEC2)

PDB	External Database	Details
Met -9	-	initiating methionine
Ala -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Val -1	-	expression tag
Gly 0	-	expression tag
Thr 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	296466.1
Non-Polymers*	Number of molecules	12
	Total formula weight	2606.2
All*	Total formula weight	299072.2

*Water molecules are not included.