8RPC

Crystal structure of PfCLK3 with TCMDC-135051

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	non-specific serine/threonine protein kinase	polymer	382	44583.5	1	UniProt (W7JM86) Pfam (PF00069)	Plasmodium falciparum (malaria parasite P. falciparum)
2	B (A)	4-[2-[5-(diethylaminomethyl)-2-methoxy-phenyl]-1~{H}-pyrrolo[2,3-b]pyridin-4-yl]-2-propan-2-yl-benzoic acid	non-polymer		471.6	1	Chemie (A1H19)
3	C (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	D, H (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	E, F, G (A)	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
6	I (A)	water	water		18.0	196	Chemie (HOH)

Sequence modifications

A: 334 - 699 (UniProt: W7JM86)

PDB	External Database	Details
Met 333	-	initiating methionine
Gly 700	-	expression tag
Ser 701	-	expression tag
Glu 702	-	expression tag
Asn 703	-	expression tag
Leu 704	-	expression tag
Tyr 705	-	expression tag
Phe 706	-	expression tag
Gln 707	-	expression tag
Gly 708	-	expression tag
His 709	-	expression tag
His 710	-	expression tag
His 711	-	expression tag
His 712	-	expression tag
His 713	-	expression tag
His 714	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	44583.5
Non-Polymers*	Number of molecules	7
	Total formula weight	976.0
All*	Total formula weight	45559.5

*Water molecules are not included.