8RNI
HLA-A*03:01 with KRAS-G12V-10mer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, A alpha chain | polymer | 277 | 31916.2 | 1 | UniProt (P04439) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | Human leukocyte antigen A,HLA-A |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11762.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | C (C) | GTPase KRas, N-terminally processed | polymer | 10 | 885.1 | 1 | UniProt (P01116) | Homo sapiens | |
| 4 | D, E, F, G, H... (A, B) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | J, K, L (A, B, C) | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A: 1 - 277 (UniProt: P04439)
B: 1 - 99 (UniProt: P61769)
C: 1 - 10 (UniProt: P01116)
| PDB | External Database | Details |
|---|---|---|
| Thr 224 | Gln 248 | conflict |
| Leu 225 | Thr 249 | conflict |
| Thr 226 | Gln 250 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Gln 17 | Asn 37 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 6 | Gly 12 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 44563.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 552.6 | |
| All* | Total formula weight | 45116.0 |
