8RMY
Transglutaminase 3 in complex with inhibitor Z-don and DH patient-derived Fab DH63-A02
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (F, C) | Antibody Fab fragment light chain IGKV4-1 | polymer | 219 | 24141.7 | 2 | Homo sapiens | ||
| 2 | C, D (A, D) | Protein-glutamine gamma-glutamyltransferase E | polymer | 464 | 51369.2 | 2 | UniProt (Q08188) Pfam (PF00868) Pfam (PF01841) | Homo sapiens (human) | Transglutaminase E,TG(E),TGE,TGase E,Transglutaminase-3,TGase-3 |
| 3 | E, F (E, B) | Antibody Fab fragment heavy chain IGHV2-5 | polymer | 221 | 23642.8 | 2 | Homo sapiens | ||
| 4 | G, H (J, K) | P6S-ONL-VAL-PRO-MLL | polymer | 5 | 602.7 | 2 | synthetic construct | ||
| 5 | I, O (A, D) | CITRATE ANION | non-polymer | 189.1 | 2 | Chemie (FLC) | |||
| 6 | J, S (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | K, L, M, P, Q... (A, D) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 8 | N (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 9 | T, U, V, W, X (F, A, D, E, B) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 199512.9 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 837.8 | |
| All* | Total formula weight | 200350.7 |
