8RK0

HCV E1/E2 homodimer complex, ectodomain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	C, A	HCV E1	polymer	123	13212.9	2	UniProt (Q81424) Pfam (PF01539) In PDB	Hepacivirus hominis
2	D, B	HCV E2	polymer	327	36466.2	2	UniProt (A9YFN8) Pfam (PF01560) In PDB	Hepacivirus hominis
3	L, E, F, G, H...	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	10	In PDB GlyTouCan (G42666HT)
4	O, P, Q, R, S...	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	8	In PDB GlyTouCan (G15407YE)
5	D, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)

Sequence modifications

C, A: 193 - 315 (UniProt: Q81424)

PDB	External Database	Details
Asp 233	Gly 42	conflict
Thr 237	Met 46	conflict

D, B: 384 - 710 (UniProt: A9YFN8)

PDB	External Database	Details
Leu 694	Gly 694	conflict
Gly 695	Leu 695	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	99358.1
Branched	Number of molecules	18
	Total formula weight	8936.3
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	108736.8

*Water molecules are not included.