8RJ7
The crystal structure of the SARS-CoV-2 receptor binding domain in complex with the neutralizing nanobody 1.29
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, I (A, C, E, G, I) | Spike protein S1 | polymer | 203 | 22726.6 | 5 | UniProt (P0DTC2) Pfam (PF09408) | Severe acute respiratory syndrome coronavirus 2 | |
| 2 | E, F, G, H, J (B, D, F, H, J) | Camel-derived nanobody 1.29 | polymer | 126 | 13348.6 | 5 | Camelus dromedarius | ||
| 3 | K, N, O, Q, U (A, C, E, G, I) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
| 4 | L, P, R, S, T (A, E, B, D, H) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 5 | M (C) | LYSINE | non-polymer | 147.2 | 1 | Chemie (LYS) | |||
| 6 | AA, BA, CA, DA, EA... (D, F, H, I, J...) | water | water | 18.0 | 887 | Chemie (HOH) |
Sequence modifications
A, C, E, G, I: 332 - 528 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Gly 330 | - | expression tag |
| Ser 331 | - | expression tag |
| Leu 529 | - | expression tag |
| Val 530 | - | expression tag |
| Pro 531 | - | expression tag |
| Arg 532 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 180375.6 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1733.5 | |
| All* | Total formula weight | 182109.2 |
