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8RHG

CryoEM structure of human rho1 GABAA receptor in complex with GABA and pregnenolone sulfate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Gamma-aminobutyric acid receptor subunit rho-1polymer47955950.25UniProt (P24046)
Pfam (PF02931)
Pfam (PF02932)
Homo sapiens (human)GABA(A) receptor subunit rho-1,GABA(C) receptor
2F, J, L, Q, V
(A, B, C, D)
GAMMA-AMINO-BUTANOIC ACIDnon-polymer103.15Chemie (ABU)
3AA, BA, G, H, M...
(E, A, B, C, D)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
4CA, I, O, T, Y
(E, A, B, C, D)
N-OCTANEnon-polymer114.25Chemie (OCT)
5K
(A)
Pregnenolone sulfatenon-polymer396.51Chemie (A8W)
6DA, P, U, Z
(E, B, C, D)
HEXANEnon-polymer86.24Chemie (HEX)
7EA
(E)
CHLORIDE IONnon-polymer35.51Chemie (CL)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight279751.2
Non-Polymers*Number of molecules26
Total formula weight4075.5
All*Total formula weight283826.7
*Water molecules are not included.

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PDB entries from 2024-11-06

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