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8RH9

CryoEM structure of human rho1 GABAA receptor in complex with pregnenolone sulfate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Gamma-aminobutyric acid receptor subunit rho-1polymer47955950.25UniProt (P24046)
Pfam (PF02931)
Pfam (PF02932)
Homo sapiens (human)GABA(A) receptor subunit rho-1,GABA(C) receptor
2AA, BA, F, G, KA...
(C, A, D, B, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
3CA, CB, DA, DB, GA...
(C, E, A, D, B)
N-OCTANEnon-polymer114.216Chemie (OCT)
4AB, EA, I, J, SA...
(E, C, A, D)
DECANEnon-polymer142.37Chemie (D10)
5K, O, QA
(A, D)
DODECANEnon-polymer170.33Chemie (D12)
6BB, FA, IA, N, NA...
(E, C, A, D, B)
HEXANEnon-polymer86.213Chemie (HEX)
7X
(B)
Pregnenolone sulfatenon-polymer396.51Chemie (A8W)
8Y
(B)
CHLORIDE IONnon-polymer35.51Chemie (CL)
9EB, FB, GB, HB, IB
(A, B, C, D, E)
waterwater18.017Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight279751.2
Non-Polymers*Number of molecules51
Total formula weight7099.0
All*Total formula weight286850.1
*Water molecules are not included.

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PDB entries from 2026-01-28

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