8RH7
CryoEM structure of human rho1 GABAA receptor in complex with GABA and estradiol in primed state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, E, B, C, D) | Gamma-aminobutyric acid receptor subunit rho-1 | polymer | 479 | 55950.2 | 5 | UniProt (P24046) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit rho-1,GABA(C) receptor |
| 2 | F, FA, G, GA, GB... (A, B, D, C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 3 | AA, AB, BB, CB, DB... (E, C, D, A, B) | N-OCTANE | non-polymer | 114.2 | 25 | Chemie (OCT) | |||
| 4 | BA, I, IA, J, JA... (E, A, B, D, C) | HEXANE | non-polymer | 86.2 | 15 | Chemie (HEX) | |||
| 5 | CA, M, MA, NB, YA (E, A, B, D, C) | ESTRADIOL | non-polymer | 272.4 | 5 | Chemie (EST) | |||
| 6 | DA, EA, FB, N, QA (E, B, D, A, C) | GAMMA-AMINO-BUTANOIC ACID | non-polymer | 103.1 | 5 | Chemie (ABU) | |||
| 7 | R (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 8 | OB, PB, QB, RB, SB (A, E, B, C, D) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 279751.2 | |
| Non-Polymers* | Number of molecules | 61 |
| Total formula weight | 8273.4 | |
| All* | Total formula weight | 288024.5 |
