8RH7
CryoEM structure of human rho1 GABAA receptor in complex with GABA and estradiol in primed state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, E, B, C, D) | Gamma-aminobutyric acid receptor subunit rho-1 | polymer | 479 | 55950.2 | 5 | UniProt (P24046) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit rho-1,GABA(C) receptor |
| 2 | F, FA, G, GA, GB... (A, B, D, C, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 3 | AA, AB, BB, CB, DB... (E, C, D, A, B) | N-OCTANE | non-polymer | 114.2 | 25 | Chemie (OCT) PubChem (356) | |||
| 4 | BA, I, IA, J, JA... (E, A, B, D, C) | HEXANE | non-polymer | 86.2 | 15 | Chemie (HEX) PubChem (8058) | |||
| 5 | CA, M, MA, NB, YA (E, A, B, D, C) | ESTRADIOL | non-polymer | 272.4 | 5 | Chemie (EST) PubChem (16757676) PubChem (177015577) PubChem (1807200) PubChem (43912931) PubChem (1807201) PubChem (44284023) PubChem (46781508) PubChem (5317222) PubChem (54403267) PubChem (56624791) PubChem (57041922) PubChem (12313788) PubChem (162947701) PubChem (58650893) PubChem (59084698) PubChem (166849971) PubChem (68014581) PubChem (68209947) PubChem (70220248) PubChem (70864205) PubChem (91740223) PubChem (101691329) PubChem (118548795) PubChem (450) PubChem (5757) PubChem (5998) PubChem (10596) PubChem (14880) PubChem (68570) PubChem (667480) PubChem (667515) PubChem (721867) PubChem (928284) PubChem (1258565) PubChem (5317221) PubChem (5745505) PubChem (6328313) PubChem (6432565) PubChem (6560352) PubChem (6603846) PubChem (6918968) PubChem (6919041) PubChem (7000012) PubChem (7004689) PubChem (7048584) PubChem (7048670) PubChem (7061189) PubChem (7067800) PubChem (126969992) PubChem (129010410) PubChem (9795489) PubChem (9811784) PubChem (9903595) PubChem (9938293) PubChem (129317336) PubChem (11869602) PubChem (11870431) PubChem (130307439) PubChem (130307440) PubChem (12313787) PubChem (12313791) PubChem (12313794) PubChem (143489158) PubChem (144605119) PubChem (145157829) PubChem (145610824) PubChem (154109755) PubChem (172873304) | |||
| 6 | DA, EA, FB, N, QA (E, B, D, A, C) | GAMMA-AMINO-BUTANOIC ACID | non-polymer | 103.1 | 5 | Chemie (ABU) PubChem (119) | |||
| 7 | R (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) | |||
| 8 | OB, PB, QB, RB, SB (A, E, B, C, D) | water | water | 18.0 | 20 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 279751.2 | |
| Non-Polymers* | Number of molecules | 61 |
| Total formula weight | 8273.4 | |
| All* | Total formula weight | 288024.5 |
