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8RH4

CryoEM structure of human rho1 GABAA receptor in complex with estradiol

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, E, B, C, D)
Gamma-aminobutyric acid receptor subunit rho-1polymer47955950.25UniProt (P24046)
Pfam (PF02931)
Pfam (PF02932)
Homo sapiens (human)GABA(A) receptor subunit rho-1,GABA(C) receptor
2F, FA, G, GA, GB...
(A, B, D, C, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
3CA, H, HA, I, IA...
(E, A, B, D, C)
N-OCTANEnon-polymer114.215Chemie (OCT)
4AB, BA, BB, DA, DB...
(C, E, D, A, B)
HEXANEnon-polymer86.225Chemie (HEX)
5AA, K, KA, LB, XA
(E, A, B, D, C)
DECANEnon-polymer142.35Chemie (D10)
6CB, EB, P, PA, S
(C, D, A, B)
ESTRADIOLnon-polymer272.45Chemie (EST)
7QA, T
(B, A)
CHLORIDE IONnon-polymer35.52Chemie (CL)
8PB, QB, RB, SB, TB
(A, E, B, C, D)
waterwater18.025Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight279751.2
Non-Polymers*Number of molecules62
Total formula weight8224.1
All*Total formula weight287975.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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