8RH2
Trimeric HSV-2G gB ectodomain in postfusion conformation with three bound HDIT102 Fab molecules.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Envelope glycoprotein B | polymer | 703 | 79378.2 | 3 | UniProt (A0A0D4CHI5) Pfam (PF17416) Pfam (PF17417) Pfam (PF00606) | Human herpesvirus 2 strain G | |
| 2 | D, H, I (H, D, F) | HDIT102 Fab heavy chain | polymer | 452 | 49310.4 | 3 | Homo sapiens | ||
| 3 | E, F, G (L, E, G) | HDIT102 Fab light chain | polymer | 212 | 22403.8 | 3 | Homo sapiens |
Sequence modifications
A, B, C: 22 - 724 (UniProt: A0A0D4CHI5)
| PDB | External Database | Details |
|---|---|---|
| Ala 553 | Val 553 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 453277.2 | |
| All* | Total formula weight | 453277.2 |
