8RGU

Arginase 2 in complex with inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Arginase-2, mitochondrial	polymer	336	36653.4	3	UniProt (P78540) Pfam (PF00491)	Homo sapiens (human)	Arginase II,Kidney-type arginase,Non-hepatic arginase,Type II arginase
2	D, E, I, J, N... (A, B, C)	MANGANESE (II) ION	non-polymer		54.9	6	Chemie (MN)
3	F, G, K, L, P... (A, B, C)	DIMETHYL SULFOXIDE	non-polymer		78.1	6	Chemie (DMS)
4	H, M, R (A, B, C)	PROLINE	non-polymer		115.1	3	Chemie (PRO)
5	S, T, U (A, B, C)	water	water		18.0	378	Chemie (HOH)

Sequence modifications

A, B, C: 22 - 341 (UniProt: P78540)

PDB	External Database	Details
Met 6	-	initiating methionine
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Gly 13	-	expression tag
Gly 14	-	expression tag
Gly 15	-	expression tag
Glu 16	-	expression tag
Asn 17	-	expression tag
Leu 18	-	expression tag
Tyr 19	-	expression tag
Phe 20	-	expression tag
Gln 21	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	109960.1
Non-Polymers*	Number of molecules	15
	Total formula weight	1143.8
All*	Total formula weight	111103.9

*Water molecules are not included.