8RG6

Arginase 2 in complex with inhibitor

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Arginase-2, mitochondrial	polymer	336	36653.4	3	UniProt (P78540) Pfam (PF00491)	Homo sapiens (human)	Arginase II,Kidney-type arginase,Non-hepatic arginase,Type II arginase
2	D, E, G, H, J... (A, B, C)	MANGANESE (II) ION	non-polymer		54.9	6	Chemie (MN)
3	F, I, L (A, B, C)	(2~{S},3~{R})-3-[3-(dihydroxyboranyl)propyl]pyrrolidine-2-carboxylic acid	non-polymer		201.0	3	Chemie (A1H0B)
4	M, N, O (A, B, C)	water	water		18.0	360	Chemie (HOH)

Sequence modifications

A, B, C: 22 - 341 (UniProt: P78540)

PDB	External Database	Details
Met 6	-	initiating methionine
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
His 11	-	expression tag
His 12	-	expression tag
Gly 13	-	expression tag
Gly 14	-	expression tag
Gly 15	-	expression tag
Glu 16	-	expression tag
Asn 17	-	expression tag
Leu 18	-	expression tag
Tyr 19	-	expression tag
Phe 20	-	expression tag
Gln 21	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	109960.1
Non-Polymers*	Number of molecules	9
	Total formula weight	932.7
All*	Total formula weight	110892.8

*Water molecules are not included.