8RFB
Cryo-EM structure of the R243C mutant of human Prolyl Endopeptidase-Like (PREPL) protein involved in Congenital myasthenic syndrome-22 (CMS22)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Prolyl endopeptidase-like | polymer | 639 | 73477.4 | 1 | UniProt (Q4J6C6) Pfam (PF02897) Pfam (PF00326) In PDB | Homo sapiens (human) | Prolylendopeptidase-like |
Sequence modifications
A: 90 - 727 (UniProt: Q4J6C6)
| PDB | External Database | Details |
|---|---|---|
| Ser 89 | - | expression tag |
| Cys 243 | Arg 243 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 73477.4 | |
| All* | Total formula weight | 73477.4 |
