8RDB
Isopenicillin N synthase N252E variant in complex with Fe and ACV under anaerobic conditions
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isopenicillin N synthase | polymer | 331 | 37578.8 | 1 | UniProt (P05326) Pfam (PF14226) Pfam (PF03171) | Aspergillus nidulans FGSC A4 | IPNS |
| 2 | B, C, D, E (A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | F (A) | FE (III) ION | non-polymer | 55.8 | 1 | Chemie (FE) PubChem (29936) | |||
| 4 | G (A) | L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE | non-polymer | 363.4 | 1 | Chemie (ACV) PubChem (20056448) PubChem (3860) PubChem (123672) PubChem (440722) PubChem (448130) PubChem (87194373) PubChem (88503887) PubChem (88503888) PubChem (92209853) PubChem (12790356) PubChem (12790357) PubChem (129360370) PubChem (129360371) PubChem (174739220) | |||
| 5 | H (A) | water | water | 18.0 | 400 | Chemie (HOH) |
Sequence modifications
A: 1 - 331 (UniProt: P05326)
| PDB | External Database | Details |
|---|---|---|
| Glu 252 | Asn 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37578.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 803.5 | |
| All* | Total formula weight | 38382.4 |
