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8RD3

Crystal structure of Saccharomyces cerevisiae Nmd4 protein bound to Upf1 helicase domain

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-dependent helicase NAM7polymer64072303.01UniProt (P30771)
Pfam (PF18141)
Pfam (PF13086)
Pfam (PF13087)
Saccharomyces cerevisiae S288C
2B
(B)
Nonsense-mediated decay protein 4polymer22125560.11UniProt (Q12129)Saccharomyces cerevisiae S288C
3C, E, F, G, H...
(A, B)
1,2-ETHANEDIOLnon-polymer62.19Chemie (EDO)
4D
(A)
SUCCINIC ACIDnon-polymer118.11Chemie (SIN)
5I
(A)
FORMIC ACIDnon-polymer46.01Chemie (FMT)
6L
(A)
MALONIC ACIDnon-polymer104.11Chemie (MLA)
7O, P
(A, B)
waterwater18.080Chemie (HOH)
Sequence modifications
A: 221 - 851 (UniProt: P30771)
PDBExternal DatabaseDetails
Met 218-initiating methionine
Ala 219-expression tag
Ser 220-expression tag
His 852-expression tag
His 853-expression tag
His 854-expression tag
His 855-expression tag
His 856-expression tag
His 857-expression tag
B: 2 - 218 (UniProt: Q12129)
PDBExternal DatabaseDetails
Gly -2-expression tag
Pro -1-expression tag
Gly 0-expression tag
Ser 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight97863.1
Non-Polymers*Number of molecules12
Total formula weight826.8
All*Total formula weight98689.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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