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8RD1

HUWE1 WWE domain in complex with compound 4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
E3 ubiquitin-protein ligase HUWE1polymer9110519.64UniProt (Q7Z6Z7)
Pfam (PF02825)
Homo sapiens (human)
2E, F, H, I, J
(A, B, C)
CHLORIDE IONnon-polymer35.55Chemie (CL)
3G, K, L
(A, C, D)
2-(2-hydroxy-2-oxoethyl)-1,3-bis(oxidanylidene)isoindole-5-carboxylic acidnon-polymer249.23Chemie (YP2)
4M, N, O, P
(A, B, C, D)
waterwater18.0378Chemie (HOH)
Sequence modifications
A, B, C, D: 1611 - 1700 (UniProt: Q7Z6Z7)
PDBExternal DatabaseDetails
Gly 1610-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight42078.3
Non-Polymers*Number of molecules8
Total formula weight924.8
All*Total formula weight43003.0
*Water molecules are not included.

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PDB entries from 2025-07-02

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