8RBF
CryoEM structure of the post-powerstroke actomyosin-5a complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Unconventional myosin-Va | polymer | 759 | 87340.1 | 1 | UniProt (Q99104) Pfam (PF00063) | Mus musculus (house mouse) | Dilute myosin heavy chain,non-muscle |
| 2 | B, C, D (B, C, D) | Actin, alpha skeletal muscle | polymer | 376 | 41888.7 | 3 | UniProt (P68135) Pfam (PF00022) | Oryctolagus cuniculus (rabbit) | Alpha-actin-1 |
| 3 | E, H, J, L (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | F, G, I, K (A, B, C, D) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 4 | Chemie (ADP) |
Sequence modifications
A: 5 - 767 (UniProt: Q99104)
B, C, D: 1 - 376 (UniProt: P68135)
| PDB | External Database | Details |
|---|---|---|
| Ala 217 | Ser 217 | engineered mutation |
| - | Asp 594 | deletion |
| - | Asp 595 | deletion |
| - | Glu 596 | deletion |
| - | Lys 597 | deletion |
| PDB | External Database | Details |
|---|---|---|
| Ace 1 | - | acetylation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 213006.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1806.0 | |
| All* | Total formula weight | 214812.1 |
