8R84

pentameric IgMFc-AIM complex focused refinement

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (N)	CD5 antigen-like	polymer	328	36100.3	1	UniProt (O43866) Pfam (PF00530)	Homo sapiens (human)
2	B, C, D, E (B, L, K, A)	Ig-like domain-containing protein	polymer	361	39715.4	4	UniProt (A0A7N5JWI9) Pfam (PF07654) UniProt (by SIFTS) (P01871)	Homo sapiens (human)
3	F (J)	Immunoglobulin J chain	polymer	169	19306.9	1	UniProt (P01591) Pfam (PF15097)	Homo sapiens (human)
4	G (C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
5	H, I (N)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)

Sequence modifications

B, L, K, A: 229 - 576 (UniProt: A0A7N5JWI9)

PDB	External Database	Details
Asp 216	-	expression tag
Tyr 217	-	expression tag
Lys 218	-	expression tag
Asp 219	-	expression tag
Asp 220	-	expression tag
Asp 221	-	expression tag
Asp 222	-	expression tag
Lys 223	-	expression tag
Gly 224	-	expression tag
Ser 225	-	expression tag
Gly 226	-	expression tag
Ser 227	-	expression tag
Gly 228	-	expression tag

J: -22 - 136 (UniProt: P01591)

PDB	External Database	Details
Glu 137	-	expression tag
Gln 138	-	expression tag
Lys 139	-	expression tag
Leu 140	-	expression tag
Ile 141	-	expression tag
Ser 142	-	expression tag
Glu 143	-	expression tag
Glu 144	-	expression tag
Asp 145	-	expression tag
Leu 146	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	214268.6
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	2
	Total formula weight	80.2
All*	Total formula weight	214773.2

*Water molecules are not included.