8R7T
Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with Alisporivir (nonimmunosuppressive analogue of Cyclosporin)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (B, A) | Peptidyl-prolyl cis-trans isomerase | polymer | 213 | 23193.3 | 2 | UniProt (A0A7J6KAD1) Pfam (PF00160) UniProt (by SIFTS) (A0A125YL73) | Toxoplasma gondii | PPIase |
| 2 | C, D (C, D) | Alisporivir | polymer | 11 | 1234.7 | 2 | BIRD (PRD_002551) | synthetic construct | |
| 3 | E, F, G, H (B, A, C, D) | water | water | 18.0 | 617 | Chemie (HOH) |
Sequence modifications
B, A: 1 - 211 (UniProt: A0A7J6KAD1)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 48856.0 | |
| All* | Total formula weight | 48856.0 |
