8R7S
Crystal Structure of Cyclophilin TgCyp23 from Toxoplasma gondii in complex with NIM811 (N-methyl-4-isoleucine cyclosporin)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peptidyl-prolyl cis-trans isomerase | polymer | 213 | 23193.3 | 2 | UniProt (A0A7J6KAD1) Pfam (PF00160) UniProt (by SIFTS) (A0A125YL73) | Toxoplasma gondii | PPIase |
| 2 | C, D (C, D) | CYCLOSPORIN A, 8 mutation | polymer | 11 | 1220.6 | 2 | BIRD (PRD_000768) | synthetic construct | |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 535 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 211 (UniProt: A0A7J6KAD1)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 48827.9 | |
| All* | Total formula weight | 48827.9 |
