8R7H

Cryo-EM structure of Human SHMT1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Serine hydroxymethyltransferase, cytosolic	polymer	486	53662.9	2	UniProt (P34896) Pfam (PF00464)	Homo sapiens (human)	SHMT,Glycine hydroxymethyltransferase,Serine methylase
2	B, C (B, C)	Serine hydroxymethyltransferase, cytosolic	polymer	486	53434.8	2	UniProt (P34896) Pfam (PF00464)	Homo sapiens (human)

Sequence modifications

A, D: 1 - 483 (UniProt: P34896)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

B, C: 1 - 483 (UniProt: P34896)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	214195.4
All*	Total formula weight	214195.4

*Water molecules are not included.