8R7B
SARS-CoV-2 NSP14 in complex with SAH and TDI-015051
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Guanine-N7 methyltransferase nsp14 | polymer | 528 | 59872.5 | 2 | UniProt (P0DTD1) Pfam (PF06471) | SARS-CoV-2 pseudovirus | Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN |
| 2 | C, D, E, K, L... (A, B) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) | |||
| 3 | F, Q (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 4 | G, H (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 5 | I, N, O, P, W (A, B) | IMIDAZOLE | non-polymer | 69.1 | 5 | Chemie (IMD) | |||
| 6 | J, X (A, B) | N-[(5-fluoranyl-1-benzofuran-4-yl)methyl]-1,5-dimethyl-4-(1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-ylsulfonyl)pyrrole-2-carboxamide | non-polymer | 471.5 | 2 | Chemie (YDT) | |||
| 7 | R, S, T, U (B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 8 | Y, Z (A, B) | water | water | 18.0 | 191 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 527 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Ala 90 | Asp 6015 | conflict |
| Ala 92 | Glu 6017 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 119745.0 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 2781.1 | |
| All* | Total formula weight | 122526.1 |
