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8R6Y

Structure of the SFTSV L protein stalled in a transcription-specific early elongation state with bound capped RNA [TRANSCRIPTION-EARLY-ELONGATION]

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RNA-directed RNA polymerase Lpolymer2084235698.51UniProt (U3GU88)
UniProt (by SIFTS) (I0DF35)
SFTS virus AH12
2B
(P)
RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*G)-3')polymer206452.01SFTS virus AH12
3C
(T)
RNA (5'-R(P*CP*UP*GP*GP*GP*CP*GP*GP*UP*AP*AP*AP*UP*GP*U)-3')polymer206480.91SFTS virus AH12
4D
(G)
RNA (5'-R(P*AP*CP*A)-3')polymer3918.61SFTS virus AH12
5E
(C)
RNA (5'-R(*(M7G)*AP*AP*A)-3')polymer185863.61SFTS virus AH12
6F
(A)
5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridinenon-polymer483.21Chemie (2KH)
PubChem (72201022)
PubChem (169450784)
7G
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
Sequence modifications
A: 1 - 2084 (UniProt: U3GU88)
PDBExternal DatabaseDetails
Ala 112Asp 112engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight255413.6
Non-Polymers*Number of molecules2
Total formula weight507.5
All*Total formula weight255921.1
*Water molecules are not included.

251801

PDB entries from 2026-04-08

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