8R6M
Crystal structure of Candida glabrata Bdf1 bromodomain 2 bound to I-BET151
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Candida glabrata strain CBS138 chromosome C complete sequence | polymer | 118 | 13773.6 | 4 | UniProt (Q6FWV7) Pfam (PF00439) | Nakaseomyces glabratus | |
| 2 | AA, BA, DA, E, EA... (C, D, A, B) | GLYCEROL | non-polymer | 92.1 | 24 | Chemie (GOL) | |||
| 3 | M, N (A) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | CA, HA, O, W (C, D, A, B) | 7-(3,5-DIMETHYL-1,2-OXAZOL-4-YL)-8-METHOXY-1-[(1R)-1-(PYRIDIN-2-YL)ETHYL]-1H,2H,3H-IMIDAZO[4,5-C]QUINOLIN-2-ONE | non-polymer | 415.4 | 4 | Chemie (1GH) | |||
| 5 | IA, JA, KA, LA (A, B, C, D) | water | water | 18.0 | 226 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 304 - 418 (UniProt: Q6FWV7)
| PDB | External Database | Details |
|---|---|---|
| Ala 301 | - | expression tag |
| Met 302 | - | expression tag |
| Gly 303 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55094.5 | |
| Non-Polymers* | Number of molecules | 30 |
| Total formula weight | 4064.2 | |
| All* | Total formula weight | 59158.6 |
